Dose delivery uncertainty estimation for probabilistic treatment planning

Position: PhD student position

Institution: Léon Bérard center, radiation therapy department, Laboratoire CREATIS

Location: Lyon, France

Application closes at: Oct 23rd, 2019 23:59


Radiotherapy treatment planning and delivery faces many uncertainties, the most important being target volume definition and uncertainty in the dose distribution delivered to the patient. Among the most important causes are setup errors, inter and intra-fraction motion of the target volume and dose calculation errors. Since decades, these uncertainties are commonly managed via margins. Therefore, the clinical target volume (CTV) delineated by the physician is traditionally expanded to a larger planning target volume (PTV).

The aim of the project is to evaluate the dose delivery uncertainty for several localizations, and to compare margin strategy vs probabilistic/robust planning.